2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

Related Products

PDF 3.95 MB

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-126857A
    5-Hydroxyomeprazole sodium
    5-Hydroxyomeprazole sodium is the major metabolite of Omeprazole (HY-B0113). Measuring 5-Hydroxyomeprazole levels in plasma can determine the extent of Omeprazole metabolism.
    5-Hydroxyomeprazole sodium
  • HY-135910S
    3,4-Dehydro Cilostazol-d11
    3,4-Dehydro Cilostazol-d11 is deuterated labeled 3,4-Dehydro Cilostazol (HY-135910). 3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3,4-Dehydro Cilostazol is used for pharmacokinetic study.
    3,4-Dehydro Cilostazol-d<sub>11</sub>
  • HY-12771S2
    O-Desmethyl Mebeverine acid-d6
    O-Desmethyl Mebeverine acid-d6 is deuterium labeled O-desmethyl Mebeverine acid.
    O-Desmethyl Mebeverine acid-d<sub>6</sub>
  • HY-136381
    N-Nitrosoglyphosate sodium
    N-Nitrosoglyphosate sodium is the nitrosamine degradation product and synthetic impurity of glyphosate herbicide.
    N-Nitrosoglyphosate sodium
  • HY-G0002S
    Lurasidone Metabolite 14326-d8
    Lurasidone Metabolite 14326-d8 is the deuterium labeled Lurasidone Metabolite 14326, which is a metabolite of Lurasidone.
    Lurasidone Metabolite 14326-d<sub>8</sub>
  • HY-Y1117R
    Melamine (Standard)
    Melamine (Standard) is the analytical standard of Melamine. This product is intended for research and analytical applications. Melamine is a metabolite?of?cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials.
    Melamine (Standard)
  • HY-100651
    Desmethylnortriptyline
    		99.95%
    Desmethylnortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression.
    Desmethylnortriptyline
  • HY-135731A
    4-Methylamino antipyrine hydrochloride
    4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever. 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties.
    4-Methylamino antipyrine hydrochloride
  • HY-136498
    T-705RMP
    T-705RMP, a phosphorylated metabolite of T-705, exhibits a very weak inhibitory effect on the IMP dehydrogenase (IMPDH) activities of the host cells, with an IC50 of 601 μM.
    T-705RMP
  • HY-156180
    DDC 3′-O-β-D glucuronide
    DDC 3′-O-β-D glucuronide (compound 5) is a drug metabolite that can prevent the fibrillization and oligomerization of Aβ42. DDC 3′-O-β-D glucuronide has potential for the research of Alzheimer's disease.
    DDC 3′-O-β-D glucuronide
  • HY-145671
    5-(3-hydroxyphenyl)-5-phenylhydantoin
    5-(3-hydroxyphenyl)-5-phenylhydantoin, is a metabolite of anti-seizure agent Phenytoin.
    5-(3-hydroxyphenyl)-5-phenylhydantoin
  • HY-G0007S1
    Omeprazole sulfone-13C,d3
    Omeprazole metabolite Omeprazole sulfone-13C,d3 is the deuterium and 13C labeled Omeprazole metabolite Omeprazole sulfone[1].
    Omeprazole sulfone-<sup>13</sup>C,d<sub>3</sub>
  • HY-135379
    Atorvastatin acetonide
    Atorvastatin acetonide is an impurity of Atorvastatin, and extracted from patent WO2011131605A1, Compound 4. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
    Atorvastatin acetonide
  • HY-135601
    Cinacalcet metabolite M4
    Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease.
    Cinacalcet metabolite M4
  • HY-143986S
    DM50 impurity 1-d9
    DM50 impurity 1-d9 is the deuterium labeled DM50 impurity 1[1].
    DM50 impurity 1-d<sub>9</sub>
  • HY-N9535A
    (R)-tert-OMe-byakangelicin
    (R)-tert-OMe-byakangelicin is a kind of furanocoumarin, which has inhibitory activity to liver drug metabolizing enzyme (DME) activity. (R)-tert-OMe-byakangelicin can be isolated from immature fruits of Angelica sinensis.
    (R)-tert-OMe-byakangelicin
  • HY-Y1314R
    Dimethyl sulfone (Standard)
    Dimethyl sulfone (Standard) is the analytical standard of Dimethyl sulfone. This product is intended for research and analytical applications. Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective.
    Dimethyl sulfone (Standard)
  • HY-135556
    Norfluoxetine
    Norfluoxetine is the active metabolite of antidepressant Fluoxetine (HY-B0102). Norfluoxetine is a selective inhibitor for serotonin uptake.
    Norfluoxetine
  • HY-113121R
    Vanillylmandelic acid (Standard)
    Vanillylmandelic acid (Standard) is the analytical standard of Vanillylmandelic acid. This product is intended for research and analytical applications. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM.
    Vanillylmandelic acid (Standard)
  • HY-113083R
    Acetaminophen glucuronide (Standard)
    Acetaminophen glucuronide (Standard) is the analytical standard of Acetaminophen glucuronide. This product is intended for research and analytical applications. Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005). Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen glucuronide (Standard)
Cat. No. Product Name / Synonyms Application Reactivity